BRP Documents and Presentations
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Aboukhalil A, Nielsen L, Saeed M, Mark RG, Clifford GD.
Reducing false alarm rates for critical arrhythmias: a large-scale
MIMIC II study.
Journal of Biomedical Informatics June 2008; 41(3):442-451.
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Clifford GD, Long WJ, Moody GB, Szolovits P.
Robust parameter extraction for decision support using multimodal
intensive care data.
Phil Trans Royal Soc A 2008; in press.
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Jia X, Malhotra A, Saeed M, Mark RG, Talmor D.
Risk factors for acute respiratory distress syndrome in patients mechanically ventilated for greater than 48 hours.
CHEST 2008 133: 853-861.
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Li Q, Mark RG, Clifford GD.
Robust heart rate estimation from multiple
asynchronous noisy sources using signal quality indices and a Kalman
Filter.
IOP Physiol Meas Jan 2008; 29(1):15-32.
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Neamatullah I, Douglass M, Lehman LH, Reisner A, Villarroel M, Long WJ, Szolovits P, Moody GB, Mark RG,
Clifford GD.
Automated De-Identification of Free-Text Medical Records.
BMC Medical Inform Decis Mak 2008; in press.
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Uzuner Ö, Sibanda TC, Luo Y, Szolovits P.
A de-identifier for medical discharge
summaries.
Artif Intell Med 2008; 42(1):13-35.
ISSN 0933-3657.
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Wolfberg AJ, DeRosier DJ, Roberts T, Syed Z, Clifford GD, Acker D, du Plessis
AJ.
A comparison of subjective and mathematical
estimations of fetal heart rate
variability.
Journal of Maternal Fetal and Neonatal Medicine
2008; 21(2):101-4.
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Zhang Y, Szolovits P.
Patient-specific learning in real time for adaptive monitoring in critical
care.
J Biomed Inform June 2008; 41(3):452-60.
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Lian J, Clifford GD, Müessig D, Lang V.
Open source model for generating RR intervals in
atrial fibrillation and
beyond.
BioMedical Engineering OnLine March 2007; 6(9):1-16.
Doi:10.1186/1475-925X-6-9.
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Sameni R, Clifford GD, Shamsollahi MB, Jutten C.
Multi-channel ECG and noise modeling:
application to maternal and fetal ECG
signals.
EURASIP Journal on Advances in Signal Processing 2007; 2007(43407):1-14.
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Sameni R, Shamsollahi MB, Jutten C, Clifford GD.
A nonlinear Bayesian filtering framework for
ECG denoising.
IEEE Trans Biomed Eng December 2007; 54(12):2172-2185.
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Uzuner Ö, Luo Y, Szolovits P.
Evaluating the state-of-the-art in automatic
de-identification.
J Am Med Inform Assoc Sept/Oct 2007; 14(5):550-563.
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Clifford GD.
A novel framework for signal representation and
source
separation.
Journal of Biological Systems June 2006; 14(2):169-183.
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He T, Clifford GD, Tarassenko L.
Application of ICA in removing artefacts from
the ECG.
Neural Comput and Applic 2006; 15(2):105-116.
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Heldt T.
Continuous blood pressure-derived cardiac output
monitoring - should we be thinking long
term?.
J Appl Physiol 2006; 101(2):373-374.
Invited editorial.
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Parlikar T, Heldt T, Verghese G.
Cycle-averaged models of cardiovascular
dynamics.
IEEE Transactions on Circuits and Systems I Fundamental Theory and
Applications 2006; 53(11):2459-2468.
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Clifford GD, Shoeb A, McSharry PE, Janz BA.
Model-based Filtering, Compression and
Classification of the
ECG.
International Journal of Bioelectromagnetism
2005; 7(1):158-161.
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Clifford GD, Tarassenko L.
Quantifying errors in spectral estimates of HRV
due to beat replacement and
resampling.
IEEE Transactions in Biomedical Engineering 2005; 52(4):630-638.
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Heldt T, Chang JL, Chen JJS, Verghese GC, Mark RG.
Cycle-averaged dynamics of a periodically driven,
closed loop circulation
model.
Control Engineering Practice 2005; 13:1163-1171.
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Mukkamala R, Reisner TA, Hojman H, Mark RG, Cohen RJ.
Continuous cardiac output monitoring by peripheral
blood pressure waveform
analysis.
IEEE Transactions on Biomedical Engineering
2005; 53(3):459-467.
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Clifford GD, Tarassenko L.
Segmenting cardiac-related data using sleep stages
increases separation between normal subjects and apnoeic
patients.
IOP Physiol Meas 2004; (25):N27-N35.
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Jager F, Moody GB, Mark RG.
Protocol to assess robustness of ST analysers: a
case study.
Physiological Measurement 2004; 25(3):629-643.
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Zong W, Moody GB, Mark RG.
Reduction of false arterial blood pressure alarms
using signal quality assessment and relationships between the
electrocardiogram and arterial blood
pressure.
Med Biol Eng Comput 2004; 42:698-706.
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McSharry PE, Clifford GD, Tarassenko L.
A dynamical model for generating synthetic
electrocardiogram
signals.
IEEE Trans Biomed Eng 2003; 50(3):289-294.
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Heldt T, Shim EB, Kamm RD, Mark RG.
Computational modeling of cardiovascular response to orthostatic stress.
J Appl Physiol 2002; 92(3):1239-1254.
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Hug C, Clifford GD.
An analysis of the errors in recorded heart rate
and blood pressure in the ICU using a complex set of signal quality
metrics.
Computers in Cardiology September 2007; 34:641-645.
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Lehman LH, Kyaw TH, Clifford GD, Mark RG.
A temporal search engine for a massive
multi-parameter clinical information
database.
Computers in Cardiology September 2007; 34:637-640.
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Long WJ.
Lessons extracting diseases from discharge
summaries.
AMIA Annu Symp Proc November 10-14 2007; 478-482.
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Parlikar TA, Heldt T, Ranade GV, Verghese GC.
Model-based estimation of cardiac output and total
peripheral
resistance.
Computers in Cardiology 2007; 34:379-382.
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Villarroel M, Saeed A, Clifford GD, Moody GB, Mark RG.
Finding relevant cases in large databases of
signals, time series, and clinical
data.
Computers in Cardiology September 2007; 34:265-268.
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Wolfberg AJ, Syed Z, Clifford GD, Tin A, Guttag J, du Plessis AJ.
Entropy of fetal EKG associated with intrapartum
fever.
New England Conference on Perinatal Research October 2007.
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Zhang Y, Silvers CT, Randolph AG.
Real-Time Evaluation of Patient Monitoring Algorithms for Critical Care at the
Bedside.
29th Annual International Conference of the IEEE on Engineering in Medicine
and Biology Society Aug 2007; 2783-2786.
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Zhang Y.
Real-Time Development of Patient-Specific Alarm Algorithms for Critical Care.
29th Annual International Conference of the IEEE on Engineering in Medicine
and Biology Society Aug 2007; 4351-4354.
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Clifford GD, Villarroel M.
Model-based determination of QT
intervals.
Computers in Cardiology 2006; 33:357-360.
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Clifford GD, Aboukhalil A, Zong W, Sun JX, Janz B, Moody GB, Mark RG.
Using the blood pressure waveform to reduce
critical false ECG
alarms.
Computers in Cardiology 2006; 33:829-832.
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Heldt T, Chernyak YB.
Analytical solution to minimal cardiovascular
model.
Computers in Cardiology September 2006; 33:785-788.
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Heldt T, Long W, Verghese GC, Szolovits P, Mark RG.
Integrating data, models, and reasoning in
critical care.
Proceedings of the 28th IEEE EMBS International Conference September
2006; 28:350-353.
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Moody GB, Koch H, Steinhoff U.
The PhysioNet/Computers in Cardiology Challenge
2006: QT interval
measurement.
Computers in Cardiology 2006; 33:313-316.
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Roberts JM, Parlikar TA, Heldt T, Verghese GC.
Bayesian networks for cardiovascular
monitoring.
Proceedings of the 28th IEEE Engineering in Medicine and Biology
Conference 2006; 205-209.
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Saeed M, Mark RG.
A novel method for the efficient retrieval of
similar multiparameter physiologic time series using Wavelet-based symbolic
representations.
AMIA Annu Symp Proc 2006; 679-683.
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Sun JX, Reisner AT, Mark RG.
A signal abnormality index for arterial blood
pressure waveforms.
Computers in Cardiology September 2006; 33:13-16.
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Zong W, Saeed M, Heldt T.
A QT interval detection algorithm based on ECG
curve length
transform.
Computers in Cardiology 2006; 33:377-380.
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Sibanda T, He T, Szolovits P, , Uzuner O.
Syntactically-informed semantic category
recognizer for discharge
summaries.
Proceedings of the Fall Symposium of the American Medical Informatics
Association AMIA November 2006; 714-718.
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Clifford GD, McSharry PE.
Method to filter ECGs and evaluate clinical
parameter distortion using realistic ECG model parameter
fitting.
Computers in Cardiology 2005; 32:715-718.
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Clifford GD, Zapanta L, Janz BA, Mietus J, Mark RG.
Segmentation of 24-hour cardiovascular activity
using ECG-based sleep/sedation and noise
metrics.
Computers in Cardiology 2005; 32:595-598.
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Douglass M, Clifford GD, Reisner A, Long WJ, Moody GB, Mark RG.
De-identification algorithm for free-text nursing
notes .
Computers in Cardiology 2005; 32:341-344.
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Heldt T, Mark RG.
Understanding post-spaceflight orthostatic
intolerance: a simulation
study.
Computers in Cardiology 2005; 32:631-634.
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Janz BA, Saeed M, Frassica J, Clifford GD, Mark RG.
Development and optimization of a critical care alert and display
(CCAD) system using retrospective ICU databases.
AMIA Annu Symp Proc 2005; .
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Janz BA, Clifford GD, Mark RG.
A multivariable analysis of sedation, activity and
agitation in critically ill patients using the Riker scale, ECG, blood
pressure and respiratory
rate.
Computers in Cardiology 2005; 32:735-738.
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Janz BA, Frassica J, Baker C, Clifford GD, Mark RG.
A new paradigm for managing information in the
ICU in response to the 80 hour work
week.
New England Surgical Society 2005; 86:118-119.
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Long WJ.
Extracting diagnoses from discharge
summaries.
AMIA Annu Symp Proc October 22-26 2005; 470-474.
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McSharry PE, Clifford GD.
A Statistical model of the sleep-wake dynamics of
the cardiac
Rhythm.
Computers in Cardiology 2005; 32:591-594.
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Parlikar TA, Verghese GC.
A simple cycle-averaged model for cardiovascular
dynamics.
Proceedings of the 27th Annual IEEE Engineering in Medicine and
Biology Society Conference 2005; 27:5490-5494.
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Samar Z, Heldt T, Verghese G, Mark R.
Model-based cardiovascular parameter estimation in
the intensive care
unit.
Computers in Cardiology 2005; 32:635-638.
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Sun JX, Reisner AT, Saeed M, Mark RG.
Estimating cardiac output from arterial blood
pressure waveforms: a critical evaluation using the MIMIC II
database.
Computers in Cardiology September 2005; 32:295-298.
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Abdala OT, Clifford GD, Saeed M, Reisner A, Moody GB, Henry I, Mark RG.
The Annotation Station: an open-source
technology for annotating large biomedical
databases.
Computers in Cardiology 2004; 31:681-685.
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Abdala OT, Saeed M.
Estimation of missing values in clinical
laboratory measurements of ICU patients using a weighted K-nearest
neighbors
algorithm.
Computers in Cardiology 2004; 31:693-696.
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Ali W, Eshelman L, Saeed M.
Identifying artifacts in arterial blood pressure
using morphogram
variability.
Computers in Cardiology September 2004; 31:697-700.
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Clifford GD, McSharry PE.
A realistic coupled nonlinear artificial ECG,
BP, and respiratory signal generator for assessing noise performance of
biomedical signal processing
algorithms.
Proc of SPIE International Symposium on Fluctuations and Noise
2004; 5467(34):290-301.
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Clifford GD, McSharry PE.
A nonlinear artificial model for generating
realistic correlated ECG, BP and
respiration.
17th international EURASIP conference June 2004; 358-360.
Biosignal 2004, Brno, Czech Republic.
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Clifford GD, McSharry PE.
Generating 24-hour ECG, BP and respiratory
signals with realistic linear and nonlinear clinical characteristics using a
nonlinear model.
Computers in Cardiology 2004; 31:709-712.
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Douglass M, Clifford GD, Reisner A, Moody GB, Mark RG.
Computer-assisted de-identification of free text
in the MIMIC II
database.
Computers in Cardiology 2004; 31:341-344.
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Healey J, Clifford GD, Kontothanassis L, McSharry PE.
An open-source method for simulating atrial
fibrillation using ECGSYN
.
Computers in Cardiology 2004; 31:425-427.
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Heldt T, Mark RG.
Scaling cardiovascular parameters for population
simulations.
Computers in Cardiology 2004; 31:133-136.
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McSharry PE, Clifford GD.
A comparison of nonlinear noise reduction and
independent component analysis using a realistic dynamical model of the
electrocardiogram.
Proc of SPIE International Symposium on Fluctuations and Noise
2004; 5467(09):78-88.
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McSharry PE, Clifford GD.
Open-source software for generating
electrocardiogram
signals.
ARXIV preprints 2004; 0406017.
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Moody GB.
Spontaneous termination of atrial fibrillation: a
challenge from PhysioNet and Computers in Cardiology
2004.
Computers in Cardiology 19-22 Sept. 2004; 31:101-104.
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Nam DS, Youn CH, Lee BH, Clifford GD, Healey J.
QoS-constrained resource allocation for a Grid-based multiple source electrocardiogram application
.
Lecture Notes in Computer Science 2004; 3043:352-359.
Information Systems and Information Technologies (ISIT) Workshop,
(Grid Session).
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Shu J, Clifford GD, Saeed M, Long WJ, Moody GB, Szolovits P, Mark RG.
An open-source, interactive Java-based system
for rapid encoding of significant events in the ICU using the Unified
Medical Language
System.
Computers in Cardiology 2004; 31:197-200.
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Wang H, Azuaje F, Clifford GD, Jung B, Black N.
Methods and tools for generating and managing
ecgML-based
information.
Computers in Cardiology 2004; 31:573-576.
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Youn CH, Nam DS, Kim B, An ES, Lee BH, Shim EB, Clifford GD.
QoS quorum-constrained resource management in
wireless grid.
Lecture Notes in Computer Science 2004; 3222:65-72.
Network and Parallel Computing, (NPC 2004), IFIP International
Conference, Wuhan, China, October 18-20.
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Youn CH, Kim B, Nam DS, Shim EB, Clifford GD, Healey J.
Resource reconfiguration scheme based on temporal
quorum status estimation in computational
grids.
Lecture Notes in Computer Science 2004; 699-707.
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Chen JJS, Heldt T, Verghese GC, Mark RG.
Analytical solution to simplified circulatory
model using piecewise linear
elastance.
Computers in Cardiology 2003; 30:45-48.
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Heldt T, Chang JL, Verghese GC, Mark RG.
Cycle-averaged models of cardiovascular dynamics.
Modelling and Control in Biomedical Systems
2003; 387-391.
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Heldt T, Oefinger MB, Hoshiyama M, Mark RG.
Circulatory response to passive and active changes
in posture.
Computers in Cardiology September 2003; 30:263-266.
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Long WJ.
Parsing free text nursing
notes.
AMIA Annu Symp Proc November 8-12 2003; 917.
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Moody GB, Jager F.
Distinguishing ischemic from non-ischemic ST
changes: the PhysioNet/Computers in Cardiology Challenge
2003.
Computers in Cardiology 2003; 30:235-237.
ISSN 0276-6547.
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Szolovits P.
Adding a medical lexicon to an English
parser.
AMIA Annu Symp Proc November 8-12 2003; 639-643.
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Zong W, Heldt T, Moody GB, Mark RG.
An open-source algorithm to detect onset of
arterial blood pressure
pulses.
Computers in Cardiology 2003; 30:259-262.
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Zong W, Moody GB, Jiang D.
A robust open-source algorithm to detect onset and
duration of QRS
complexes.
Computers in Cardiology 2003; 30:737-740.
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Francis SE.
Continuous estimation of cardiac output and arterial blood resistance
from arterial blood pressure using a third-order Windkessel model.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2007.
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Jia X.
Risk factors for acute lung injury and acute respiratory distress
syndrome in patients mechanically ventilated for greater than 48 hours.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2007.
-
Li SX.
Probabilistic network models in cardiovascular monitoring.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2007.
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Parlikar TA.
Modeling and Monitoring of Cardiovascular Dynamics for Patients in
Critical Care.
Doctoral dissertation, Department of Electrical Engineering and
Computer Science, Massachusetts Institute of Technology, Cambridge, MA, June
2007.
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Saeed M.
Temporal Pattern Recognition in Multiparameter ICU Data.
Doctoral dissertation, Department of Electrical Engineering and
Computer Science, Massachusetts Institute of Technology, Cambridge, MA, June
2007.
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Shavdia D.
Septic shock: providing early warnings using logistic regression
models.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2007.
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Trepetin S.
Privacy in context: the costs and benefits of a
new deidentification method.
Doctoral dissertation, Department of Electrical Engineering and
Computer Science, Massachusetts Institute of Technology, Cambridge, MA, 2006.
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Zamanian SA.
Modeling and simulating human cardiovascular response to
acceleration.
M.S. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2007.
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Hug C.
Predicting the risk and trajectory of intensive
care patients using survival models.
M.S. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2006.
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Neamatullah I.
Automated de-identification of free text medical records.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2006.
-
Oefinger MB.
Monitoring transient repolarization segment
morphology deviations in mouse ECG.
Doctoral dissertation, Harvard-MIT Division of Health Sciences and
Technology, Massachusetts Institute of Technology, Cambridge, MA, September
2006.
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Roberts JM.
Bayesian networks for cardiovascular
monitoring.
M.S. thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2006.
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Sibanda T.
Was the patient cured? Understanding semantic
categories and their relationships in patient
records.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2006.
-
Sun J.
Cardiac output estimation using arterial blood pressure waveforms.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2006.
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Abdala OT.
The Annotation Station: an open source technology
for data visualization and annotation of large biomedical
databases.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2005.
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Douglass M.
Computer-assisted de-identification of free-text
nursing notes.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, February 2005.
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Kyaw TH.
Formatting and searching a massive,
multi-parameter clinical information
database.
Master's thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2005.
-
Renjifo CA.
Exploration, processing, and visualization of
physiological signals from the ICU.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2005.
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Samar Z.
Cardiovascular parameter estimation using a
computational model.
M.S. thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2005.
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Shu J.
Free text phrase encoding and information
extraction from medical notes.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2005.
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Zapanta LF.
Heart rate variability in mice with coronary heart
disease.
M.S. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2005.
-
Heldt T.
Computational Models of Cardiovascular Function
During Orthostatic Stress.
Doctoral dissertation, Harvard-MIT Division of Health Sciences and
Technology, Massachusetts Institute of Technology, Cambridge, MA, September
2004.
-
Thorn K.
Characterization of intravenous medication
administration in an intensive care
unit.
M.S. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2004.
-
Chen JJS.
Analytical solution to a simplified circulatory model using piecewise
linear elastance function.
M.S. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, July 2003.
-
Levine JM.
De-identification of ICU patient
records.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2003.
-
Oefinger MB.
System for remote multichannel real-time monitoring of mouse ECG
via the Internet.
M.S. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2003.
-
Zhang Y.
Real-time analysis of physiological data and
development of alarm algorithms for patient monitoring in the Intensive Care
Unit.
M.S. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, September
2003.
-
Chang JL.
Cycle-averaged models of cardiovascular dynamics.
M.Eng. Thesis, Department of Electrical Engineering and Computer
Science, Massachusetts Institute of Technology, Cambridge, MA, June 2003.
-
Clifford GD, Azuaje F, McSharry PE (eds.).
Advanced Methods and Tools for ECG Analysis, volume 1 of
Engineering in Medicine and Biology.
1 edition. Norwood, MA, USA: Artech House, October 2006.
ISBN 1-58053-966-1.
-
Clifford GD, Oefinger MB.
Ch 2: ECG Acquisition, Storage, Transmission, and Representation in
Advanced Methods and Tools for ECG Analysis, volume 1 of Engineering in
Medicine and Biology.
1 edition. Norwood, MA, USA: Artech House, October 2006;
27-53.
ISBN 1-58053-966-1.
-
Clifford GD.
Ch 3: ECG Statistics, Noise, Artifacts, and Missing Data in Advanced
Methods and Tools for ECG Analysis, volume 1 of Engineering in Medicine and
Biology.
1 edition. Norwood, MA, USA: Artech House, October 2006;
55-99.
ISBN 1-58053-966-1.
-
Clifford GD.
Ch 5: Linear Filtering MethodsAdvanced Methods and Tools for ECG
Analysis, volume 1 of Engineering in Medicine and Biology.
1 edition. Norwood, MA, USA: Artech House, October 2006;
135-170.
ISBN 1-58053-966-1.
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McSharry PE, Clifford GD.
Ch 4: Models for ECG and RR interval Processes in Advanced Methods
and Tools for ECG Analysis, volume 1 of Engineering in Medicine and Biology.
1 edition. Norwood, MA, USA: Artech House, October 2006;
101-133.
ISBN 1-58053-966-1.
-
McSharry PE, Clifford GD.
Ch 6: Nonlinear Filtering Methods in Advanced Methods and Tools for
ECG Analysis, volume 1 of Engineering in Medicine and Biology.
1 edition. Norwood, MA, USA: Artech House, October 2006;
171-196.
ISBN 1-58053-966-1.
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Reisner AT, Clifford GD, Mark RG.
Ch 1: The Physiological Basis of the Electrocardiogram in Advanced
Methods and Tools for ECG Analysis, volume 1 of Engineering in Medicine and
Biology.
1 edition. Norwood, MA, USA: Artech House, October 2006;
1-25.
ISBN 1-58053-966-1.
BRP Documents and Presentations
Last modified
2008-07-25